2nd International Symposium on Medication Related Osteonecrosis of the Jaws (MRONJ) in Copenhagen 02 November 2018 – Copenhagen – Denmark

Ievgen I. Fesenkoa more
a Ievgen I. Fesenko

PhD, Assistant Professor Kyiv, Ukraine i.i.fesenko@dtjournal.org Instagram: dr_eugenfesenko

January 31, 2019


J Diagn Treat Oral Maxillofac Pathol 2021;5–7.

Under a Creative Commons license


Fesenko II. 2nd international symposium on medication related osteonecrosis of the jaws (MRONJ) in Copenhagen 02 November 2018 – Copenhagen – Denmark. J Diagn Treat Oral Maxillofac Pathol 2021;3(1):5–7.


Contents: Article |  Event Presentation | Conclusion of Event | References (12)


“Good directors don't answer questions with their work. They generate debate and create discussion.”

─ Alejandro Gonzalez Inarritu

Film director who won 5 Oscars


2nd International Symposium on Medication Related Osteonecrosis of the Jaws (MRONJ) in Copenhagen became a much needed continuation of an amazing initiative of the Department of Oral Maxillofacial Surgery of Rigshospitalet (Copenhagen University Hospital) [1]. And it would be completely impossible without those famous scientists like Morten Schiodt (Denmark), Sven Otto (Germany), Alberto Bedogni (Italy), Ourania Nicolatou-Galitis (Greece), Stefano Fedele (England), Roman Guggenberger (Switzerland), Bente Brokstad Herlofson (Norway), Camilla Ottesen (Denmark), Sanne Werner Moller Andersen (Denmark), and Thomas Kofod (Denmark) [2].


Dr. Sven Otto (editor) and Dr. Stefano Fedele (co-editor of the chapter) made an enormous contribution in the field of diagnostics and treatment of MRONJ by publishing the textbook Medication-Related Osteonecrosis of the Jaws: Bisphosphonates, Denosumab, and New Agents (Fig 1) in 2015 [3]. And impact of those specialists on Symposium was terrific.

Event Presentation


Dr. Morten Schiodt, as Chairman of the Symposium (Fig 2) [4], with his team has done a crucial and titanic work in organization the meeting and it`s state of the art performance.


Dr. Schiodt`s CV includes a position of a Chairman of the Department of Oral & Maxillofacial Surgery, Copenhagen University Hospital 2001-2011. He served as President of the Danish Association Oral & Maxillofacial Surgery for 6 years (1984-1986 and 1989-1991), President of the Danish Society of Oral & Maxillofacial Surgery for 6 years (1996-2002), Associate Professor in University of California (San Francisco, USA, 1986-1989). Moreover, Dr. Schiodt is a scientific reviewer of 13 international Journals and director of SICCA-Denmark founded in 2003, part of NIH-funded multicenter project leading to new classification of Sjogren's Syndrome. Dr. Schiodt is author and co-author of 186 publications [5-9].

Present positions of Dr. Schiodt [2]:


  • Senior Maxillofacial Consultant at Department of Oral & Maxillofacial Surgery, Copenhagen University Hospital (Rigshospitalet), Denmark.

  • 2003 – now: Director of SICCA Denmark. Part of multinational Sjogren project.

  • 2010 – now: Director of Osteonecrosis Research at Copenhagen University Hospital, Denmark.

  • 2010 – now: Director of Copenhagen ONJ Cohort (288 patients).

  • 2011 – now: Scandinavian Coordinator for Scandinavian ONJ Database (Amgen XGEVA-363-study). 1000 patients enrolled.

  • 2014 – now: European Lead Investigator for a Global Multicenter Case registry ONJ study (Amgen 2010-1102 study), 64 sites, 275 patients enrolled.

Such a huge academic and organizational experience of the Chairman together with a fantastic work and performance of every speaker continue to make that annual Symposium a new brightly lit road in the darkness of important problems in diagnostics, treatment and preventive measures of MRONJ.


Finally, it`s an extremely important aspect of every scientific meeting – a place and atmosphere of the event. A lot of studies (Porto et al, 2014; Dimou et al, 2016; Rosenbluth et al, 2017) proved that oral and maxillofacial surgeons are staying in the group with an increased level of burnout syndrome [10-12]. And it`s so helpful for colleagues upon the event to visit and relax in a magnificent Copenhagen (Fig 3) with its history, design, spirit, and amazing people.

Conclusios of Event

The 2nd International Symposium on MRONJ in Copenhagen teaches us the next important things:


  1. Perfect location of the Symposium (in the heart of Europe) makes it an extremely comfortable for quick flying from other European countries (2-2.5 hours Kyiv-Copenhagen fly).

  2. Registration fees for a one-day MRONJ Symposium was not huge (140 euro for dentists/doctors/others and 90 euro for students/trainees), what makes it much more affordable than 4-days meetings.

  3. Such a narrow-field Symposium can precisely help you to find a world famous opinion leaders, possible co-authors, advisors, mentors, and friends.

  4. When opinion leaders in some field like Dr. Morten Schiodt and Dr. Sven Otto are organizing a scientific meeting, its success is guaranteed.

  5. Warm atmosphere of the Symposium and beauty of the Copenhagen helped for medical specialists to decrease the sings of burnout syndrome after a hard work.

And a final opinion is next: the 3rd MRONJ Symposium in 2020 should be definitely visited not only because of extremely beautiful Copenhagen, but according to huge actuality and so much needed cutting-edge MRONJ events.

Ievgen I. Fesenko, PhD, Assistant Professor

Kyiv, Ukraine

email: i.i.fesenko@dtjournal.org

Instagram: dr_eugenfesenko

References (12)

  1. 2nd International Symposium on Medication Related Osteonecrosis of the Jaw (MRONJ) in Copenhagen. Available at: Link Access January 09, 2019.

  2. Speakers. Available at: Link Access January 09, 2019.

  3. Otto S. Medication-related osteonecrosis of the jaws: bisphosphonates, Denosumab, and new agents. 1st ed. Berlin: Springer; 2015.

  4. Official materials of the 2nd International Symposium on MRONJ in Copenhagen. Access October 10, 2018.

  5. Aljohani S, Gaudin R, Weiser J, Tröltzsch M, Ehrenfeld M, Kaeppler G, Smeets R, Otto S. Osteonecrosis of the jaw in patients treated with denosumab: a multicenter case series. J Craniomaxillofac Surg 2018;46(9):1515–25. Crossref

  6. Fung P, Bedogni G, Bedogni A, Petrie A, Porter S, Campisi G, Bagan J, Fusco V, Saia G, Acham S, Musto P, Petrucci MT, Diz P, Colella G, Mignogna MD, Pentenero M, Arduino P, Lodi G, Maiorana C, Manfredi M, Hallberg P, Wadelius M, Takaoka K, Leung YY, Bonacina R, Schiødt M, Lakatos P, Taylor T, De Riu G, Favini G, Rogers SN, Pirmohamed M, Nicoletti P; GENVABO Consortium, Fedele S. Time to onset of bisphosphonate-related osteonecrosis of the jaws: a multicentre retrospective cohort study. Oral Dis 2017;23(4):477–83. Crossref

  7. Acquavella J, Ehrenstein V, Schiødt M, Heide-Jørgensen U, Kjellman A, Hansen S, Wexell CL, Herlofson BB, Noerholt SE, Ma H, Ӧhrling K, Hernandez RK, Sørensen HT. Design and methods for a Scandinavian pharmacovigilance study of osteonecrosis of the jaw and serious infections among cancer patients treated with anti-resorptive agents for the prevention of skeletal related events. Clin Epidemiol 2016;8:267–72. Crossref

  8. Yazdi P, Schiodt M. Dentoalveolar trauma and minor trauma as precipitating factors for medication-related osteonecrosis of the jaws (ONJ): a retrospective study of 149 patients from the Copenhagen ONJ Cohort. Oral Surg Oral Med Oral Pathol Oral Radiol 2015;119(4):416–22. Crossref

  9. Schiodt M, Reibel J, Oturai P, Kofod T. Comparison of nonexposed and exposed bisphosphonate-induced osteonecrosis of the jaws: a retrospective analysis from the Copenhagen cohort and a proposal for an updated classification system. Oral Surg Oral Med Oral Pathol Oral Radiol 2014;117(2):204–13. Crossref

  10. Porto GG, Carneiro SC, Vasconcelos BC, Nascimento MM, Leal JL. Burnout syndrome in oral and maxillofacial surgeons: a critical analysis. Int J Oral Maxillofac Surg 2014;43(7):894–9. Crossref

  11. Dimou FM, Eckelbarger D, Riall TS. Surgeon burnout: a systematic review. J Am Coll Surg 2016;222(6):1230–9. Crossref

  12. Rosenbluth SC, Freymiller EG, Hemphill R, Paull DE, Stuber M, Friedlander AH. Resident well-being and patient safety: recognizing the signs and symptoms of burnout. J Oral Maxillofac Surg 2017;75(4):657-9. Crossref