Vol. 1, Issue 3–4

Volume 1, Issue 3–4

Pages 175–182

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ORIGINAL
ONCOLOGIC

Question of the Etiology of Malignant Neoplasms

Oleksii O. Tymofieieva, ... Mariia O. Yarifad more
a Oleksii O. Tymofieiev

Chair of the Department of Maxillofacial Surgery, Shupyk National Nedical Academy of Postgraduate Education, Kyiv, Ukraine (Prof, ScD). Corresponding author. Department of Maxillofacial Surgery, Shupyk NMAPE, 4-a Pidvysotskogo Street, Kyiv 01103, Ukraine. Tel., fax: +38 (044) 528 35 17. E-mail address: tymofeev@gmail.com (O.O. Tymofieiev) Instagram: oleksii.tymofieiev; dt_journal

b Oleksandr O. Tymofieiev

Associate Professor of the Dentistry Department of Shupyk National Medical Academy of Postgraduate Education (Assoc Prof, ScD)

c Natalia O. Ushko

Associate Professor of the Maxillofacial Surgery Department of Shupyk National Medical Academy of Postgraduate Education (Assoc Prof, PhD)

d Mariia O. Yarifa

Associate Professor of Surgical Dentistry and Maxillofacial Surgery Department of PHEE “Kyiv Medical University” (PhD)

December 28, 2017

https://doi.org/10.23999/j.dtomp.2017.3-4.11

J Diagn Treat Oral Maxillofac Pathol 2017;1:175−82.

Under a Creative Commons license

How to cite this article

Tymofieiev OO, Tymofieiev OO, Ushko NO, Yarifa MO. Question of the etiology of malignant neoplasms. J Diagn Treat Oral Maxillofac Pathol 2017;1(3−4):175−82.

ABSTRACT

Purpose: To determine the severity of potentiometric parameters in patients with malignant neoplasms of the oral mucosa and the presence of metal inclusions in the form of non-removable dentures made of dissimilar metals and their alloys.

 

Methods: We examined of potentiometric parameters in 39 patients with metallic inclusions in the oral cavity, in which malignant tumors of the mucous membrane of the oral cavity (tongue, palate, mucous membrane of the alveolar process and the bottom of the oral cavity) were detected. All subjects were between the ages of 40 and 68 years.

 

Results: High potentiometric indicators were revealed in patients with non-removable metal dentures, which are made of dissimilar metals and their alloys. The presence of defects in the lining of dentures, as well as metal parts of a non-removable structure or metal protective coating ("bald zones") increase the potentiometric parameters and increase the risk of malignant neoplasms of the mucous membranes.

 

Conclusions: The presence of metal inclusions in the oral cavity in the form of permanent dentures can be one of the reasons for the development of malignant neoplasms of the mucous membranes. A significant increase (more than 3 times higher than the normal values) of potentiometric parameters in patients with malignant tumors of the mucous membranes with metallic inclusions in the oral cavity is observed not only between the metals of immovable dentures, but also between the metal denture and the mucosa of the alveolar process of the jaw, between different parts of the mucous membranes of the alveolar process.